Clinical Trials
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Principal Investigator:
Tamim M. Nazif, MDThis prospective, multicenter trial is looking at the investigative device called the ACURATE Transcatheter Aortic Valve System for TAVR to see if it is safe and effective in treating patients with severe symptomatic native aortic stenosis. The ACURATE Transcatheter Aortic Valve System for TAVR is designed for iliofemoral access and delivery of a self-expanding implant that restores competency in a sclerotic aortic valve. To implant the device, a surgical incision is made in the femoral vein (incision in the upper leg between the knee and the hip). A catheter is advanced into the heart access... -
Principal Investigator:
Kelly Marie Axsom, MDThe ALLEVIATE-HF study is a prospective, randomized, multi-site, interventional, investigational device exemption (IDE) study. The purpose of the study is to gain experience with utilization of an integrated device diagnostic-based risk stratification algorithm to guide patient care in subjects with NYHA class II and III heart failure. The study will utilize the market-released Reveal LINQ Insertable Cardiac Monitor with an investigational ALLEVIATE-HF RAMware download. The study will enroll up to 300 subjects at up to 30 sites in the US and will characterize the safety of the patient... -
Principal Investigator:
Susheel Kumar Kodali, MDThis is designed for patients with severe, symptomatic mitral regurgitation who are not candidates for conventional mitral repair. -
Principal Investigator:
Susheel Kumar Kodali, MDThe goal of this early feasibility study is to gain initial insight into the basic safety and performance of transluminal (through the blood vessels) implantation of the PASCAL Systems implant (composed of man-made materials). We are trying to evaluate the safety and performance of the PASCAL System with Optimal Medical Therapy (OMT) (also known as standard of care) compared to OMT alone in participants with symptomatic severe tricuspid regurgitation who may not be ideal candidates for tricuspid valve surgery (tricuspid valve repair that is performed via open-heart surgery) and may be... -
Principal Investigator:
Muredach Patrick Reilly, MDAs an academic medical center, we are always working to improve patient and population health. One way that research is supported here is through the Columbia University Biobank (CUB). A biobank is a collection of biological samples and health data that is collected during a patient's medical care. The goal of a biobank is to provide materials for researchers to use in their scientific studies of health conditions such as cancer, heart disease, and diabetes. People who participate in a biobank help researchers find treatments and cures, and they also help their community benefit from improved... -
Principal Investigator:
Andrew J. Einstein, MD, PhD*COVID Cohort* We are seeking patients that have had a pre-COVID heart CT scan (Coronary Computed Tomography Angiography) that was performed at Columbia University Irving Medical Center/NewYork-Presbyterian Hospital before March of 2020. For this study, half of patients will be required to have had COVID-19 symptoms (e.g., fever, cough, shortness of breath) and would have tested positive for COVID-19 (by an FDA-approved test). The other half will not have had a prior diagnosis of COVID-19. If you enroll in the study, you will be given a CT, asked to provide a blood sample as well as answer... -
Principal Investigator:
Andrew J. Einstein, MD, PhD*Non-COVID* We are seeking patients that have had a pre-COVID heart CT scan (Coronary Computed Tomography Angiography) that was performed at Columbia University Irving Medical Center/NewYork-Presbyterian Hospital before March of 2020. For this study, half of patients will be required to have had COVID-19 symptoms (e.g., fever, cough, shortness of breath) and would have tested positive for COVID-19 (by an FDA-approved test). The other half will not have had a prior diagnosis of COVID-19. If you enroll in the study, you will be given a CT, asked to provide a blood sample as well as answer the... -
Principal Investigator:
Edward Felix Lin, MDThe purpose of this study is to collect data about congestive heart failure over several months from patients at home and to assess the ability of a newly developed wireless device to accurately measure changes in the heart and lungs due to CHF. A secondary aim is to determine if the device may predict hospitalizations before they occur. -
Principal Investigator:
Marwah Abdalla, MDThe Center for Behavioral Cardiovascular Health (CBCH) is conducting a research study to examine the impacts on blood pressure when it is measured with and without someone in the room with you. Two-part screening to determine eligibility for this study involves a) answering questionnaires and b) measuring your arm circumference. Participation in the research study involves 1-2 study visits, wearing a wrist activity monitoring device for 8 days, wearing a blood pressure measurement device for 24 hours and taking your blood pressure 4 times a day for 7 days, receiving daily text messages and... -
Principal Investigator:
Sahil A. Parikh, MDThis study aims to collect information about the symptoms and treatments of patients who have severely clogged arteries and are treated with commercially available Boston Scientific Corporation drug-eluting devices marketed for the treatment of lesions located in the peripheral vasculature. Participation in the study is expected to last for up to two (2). If you choose to be part of this research, we will ask you to be involved in routine follow-up visits at 6 months, 1 year, and every year thereafter for up to 2 years. Additionally, you may be asked to complete a survey before being treated...