Clinical Trials
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Principal Investigator:
Torsten Peter Vahl, MDThe objective of the study is to evaluate the safety and efficacy of the JenaValve Pericardial TAVR system when treating patients with aortic regurgitation. Aortic Regurgitation is a condition that develops when the heart's aortic valve does close tightly, therefore the blood leaks back into the heart chamber. The JenaValve Pericardial TAVR system will be used to treat this condition and restore proper flow blood. Treatment of aortic regurgitation with the JenaValve provides a controlled valve release and deployment during the entire implantation procedure under beating heart conditions,... -
Principal Investigator:
Muredach Patrick Reilly, MDAs an academic medical center, we are always working to improve patient and population health. One way that research is supported here is through the Columbia University Biobank (CUB). A biobank is a collection of biological samples and health data gathered during a patient's medical care. Participants in a biobank help researchers find treatments and cures, benefiting their community through improved health. It takes everyone working together to make important medical discoveries! Participation is completely voluntary and involves just a few steps: 1. Be a patient of CUIMC/NYP. 2. Review and... -
Principal Investigator:
Vivian Gar-Yan Ng, MDThe purpose of this study is to find out, in patients with CAD who had successful TAVR with a balloon expandable heart valve, whether restoring blood flow to all blocked or narrowed arteries via PCI using coronary stents (metal scaffold) is better than treating the coronary artery disease with medications only following TAVR. The study will also compare measurements of hemodynamics (blood flow and blood pressure) that are taken during on-table procedures (TAVR and PCI) with those taken by echocardiography (heart ultrasound). These measurements are all taken as a part of standard practice for... -
Principal Investigator:
Andrew J. Einstein, MD, PhDWe are seeking patients that have had a pre-COVID heart CT scan (Coronary Computed Tomography Angiography) that was performed at Columbia University Irving Medical Center/NewYork-Presbyterian Hospital before March of 2020. For this study, half of patients will be required to have had COVID-19 symptoms (e.g., fever, cough, shortness of breath) and would have tested positive for COVID-19 (by an FDA-approved test). The other half will not have had a prior diagnosis of COVID-19. If you enroll in the study, you will be given a CT, asked to provide a blood sample as well as answer the study... -
Principal Investigator:
Andrew J. Einstein, MD, PhDWe are seeking patients that have had a pre-COVID heart CT scan (Coronary Computed Tomography Angiography) that was performed at Columbia University Irving Medical Center/NewYork-Presbyterian Hospital before March of 2020. For this study, half of patients will be required to have had COVID-19 symptoms (e.g., fever, cough, shortness of breath) and would have tested positive for COVID-19 (by an FDA-approved test). The other half will not have had a prior diagnosis of COVID-19. If you enroll in the study, you will be given a CT, asked to provide a blood sample as well as answer the study... -
Principal Investigator:
Sahil A. Parikh, MDThis study aims to collect information about the symptoms and treatments of patients who have severely clogged arteries and are treated with commercially available Boston Scientific Corporation drug-eluting devices marketed for the treatment of lesions located in the peripheral vasculature. Participation in the study is expected to last for up to two (2) years. If you choose to be part of this research, we will ask you to be involved in routine follow-up visits at 6 months, 1 year, and every year thereafter for up to 2 years. Additionally, you may be asked to complete a survey before being... -
Principal Investigator:
Daichi Shimbo, MDThe measurement of blood pressure used to determine if a person has high blood pressure (also known as hypertension) and whether their blood pressure is controlled while taking medications that lower blood pressure. For many people, blood pressure levels are different when measured in a provider's office versus during normal daily activities outside of the office. There are two ways to measure blood pressure outside of the office: ambulatory blood pressure monitoring (ABPM) and home blood pressure monitoring (HBPM). The best approach to measure blood pressure outside of the office is unclear... -
Principal Investigator:
Frederick Arthur Ehlert, MDThe purpose of this registry is to collect information over time about how Medtronic products are working and/or the outcome of the treatment. The registry will be used to support post-market surveillance/monitoring activities and post-approval studies (e.g., to collect safety and performance information). In addition, it will be used to obtain clinical evidence for the development and improvement of medical devices, therapies, device guidelines and patient services/solutions. The Registry data is intended to benefit and support interests of patients, hospitals, clinicians, regulatory bodies... -
Principal Investigator:
Angelo Bartolo Biviano, MDThe purpose of this study is to assess whether it is safe and effective to stop oral anticoagulation medication (a blood-thinning medication) during prolonged periods of normal heart rhythm in participants with infrequent episodes of atrial fibrillation (AF). Atrial fibrillation (AF) is the most common abnormal heart rhythm and is associated with an increased risk of stroke, heart failure, and death. -
Principal Investigator:
Ajay J. Kirtane, MDWe are doing this study to evaluate the real-world use of the Paradise Ultrasound Renal Denervation System indicated for patients who are unable to lower their blood pressure with lifestyle changes and medication. This is an FDA approved device. Involvement in the study is expected to last approximately 60 months. Patients will be asked to collect blood pressure (BP) at home, to help us understand how ultrasound renal denervation impacts their blood pressure over time. Patients will receive home BP monitor device for the entire duration of the study and will be trained how to use it.