Publications
Select Primary Publications
Tzimas C, Rau CD, Buergisser PE, Jean-Louis G Jr, Lee K, Chukwuneke J, Dun W, Wang Y, Tsai EJ. WIPI1 is a conserved mediator of right ventricular failure. JCI Insight. 2019;4(1):e122929. https://doi.org/10.1172/jci.insight.122929. PMID: 31021818.
Peters A, Caroline M, Zhao H, Baldwin MR, Forfia PR, Tsai EJ. Initial right ventricular dysfunction severity identifies severe peripartum cardiomyopathy phenotype with worse early and overall outcomes: a 24-year cohort study. J Am Heart Assoc. 2008;7(9). Pii:e008378. https://doi.org/10.1161/JAHA.117.008378. PMID: 29686029.
Trappanese DM, Liu Y, McCormick RC, Cannavo A, Nanayakkara G, Baskharoun MM, Jarrett H, Woitek FJ, Tillson DM, Dillon AR, Recchia FA, Balligand JL, Houser SR, Koch WJ, Dell'Italia LJ, Tsai EJ. Chronic b1-adrenergic blockade enhances myocardial b3-adrenergic coupling with nitric oxide-cGMP signaling in a canine model of chronic volume overload: new insights into mechanisms of cardiac benefit with selective b1-blocker therapy. Basic Research in Cardiology. 2015; 110(1):456. PMID 25480109.
Liu Y, Dillon AR, Tillson M, Makarewich C, Nguyen V, Dell'Italia L, Sabri AK, Rizzo V, Tsai EJ. Volume overload induces differential spatiotemporal regulation of myocardial soluble guanylyl cyclase in eccentric hypertrophy and heart failure. Journal of Molecular and Cellular Cardiology. 2103;60:72-83. PMID 23567617.
Tsai EJ, Liu Y, Koitabashi N, Bedja D, Danner T, Jasmin JF, Lisanti MP, Friebe A, Takimoto E, Kass DA.
Pressure-overload-induced subcellular relocalization/oxidation of soluble guanylyl cyclase in the heart modulates enzyme stimulation. Circulation Research. 2012;110(2):295-303. PMID: 22095726.
Tsai EJ, Kass DA. Cyclic GMP signaling in cardiovascular pathophysiology and therapeutics. Pharmacology & Therapeutics. 2009;122(3):216-38. PMID 19306895.
Select Collaborative Publications
Luongo TS, Lambert JP, Gross P, Nwokedi M, Lombardi AA, Shanmughapriya S, Carpenter AC, Kolmetzky D, Gao E, van Berlo JH, Tsai EJ, Molkentin JD, Chen X, Madesh M, Houser SR, Elrod JW. The mitochondrial Na+/Ca2+ exchanger is essential for Ca2+ homeostasis and viability. Nature. 2017;545(7652):93-90. PMID 28445457.
Ware JS, Li J, Mazaika E, Yasso CM, DeSouza T, Cappola TP, Tsai EJ, Hilfiker-Kleiner D, Kamiya CA, Mazzarotto F, Cook SA, Halder I, Prasad SK, Pisarcik J, Hanley-Yanez K, Alharethi R, Damp J, Hsich E, Elkayam U, Sheppard R, Kealey A, Alexis J, Ramani G, Safirstein J, Boehmer J, Pauly DF, Wittstein IS, Thohan V, Zucker MJ, Liu P, Gorcsan J 3rd, McNamara DM, Seidman CE, Seidman JG, Arany Z. Shared Genetic Predisposition in Peripartum and Dilated Cardiomyopathies. The New England Journal of Medicine. 2016;374(3):233-41. PMID:26735901.
Hariharan N, Quijada P, Mohsin S, Joyo A, Samse K, Monsanto M, De La Torre A, Avitabile D, Ormachea L, McGregor MJ, Tsai EJ, Sussman MA. Nucleostemin rejuvenates cardiac progenitor cells and antagonizes myocardial aging. Journal of the American College of Cardiology. 2015; 65(2):133-47. PMID: 25593054
Lal H, Ahmad F, Zhou J, Yu JE, Vagnozzi RJ, Guo Y, Yu D, Tsai EJ, Woodgett J, Gao E, Force T. Cardiac fibroblast glycogen synthase kinase-3β regulates ventricular remodeling and dysfunction in ischemic heart. Circulation. 2014; 130(5):419-30. PMID: 24899689
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