Luigi Pirelli, MD, FACC

Cardiac Surgery
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Overview

Luigi Pirelli, MD earned his medical degree from the University of Milan, Italy. He completed his cardiac surgery training at the University of Milan and New York University. Dr. Pirelli's expertise include transcatheter valve therapies and surgical valve repairs.

Areas of Expertise / Conditions Treated

  • Mitral Valve Repair
  • Transcatheter Aortic Valve (TAVR)
  • Transcatheter Edge to Edge Repair (TEER)
  • Transcatheter Mitral Valve Replacement (TMVR)
  • Transcatheter Tricuspid Valve Replacement (TTVR)
  • Transcatheter Valve Therapies
  • Valve Surgery
  • Valvular Heart Disease

Academic Appointments

  • Assistant Professor of Surgery at CUMC

Hospital Affiliations

  • NewYork-Presbyterian / Columbia University Irving Medical Center

Languages

  • Italian

Gender

  • Male

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Virtual Visits/Telehealth

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Phone Appointments

New and Existing Patients:
(212) 305-4134

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Location(s)

CUIMC/Milstein Hospital Building
177 Ft. Washington Avenue
New York, NY 10032
Primary
Open location in Google Maps

Insurance Accepted

Aetna

  • Aetna Signature Administrators
  • EPO
  • NYP Employee Plan
  • NY Signature
  • Student Health

Affinity Health Plan

  • Medicaid Managed Care

Amerigroup of New Jersey

  • New Jersey Services (Medicaid Managed Care)

Cigna

  • EPO
  • Great West (National)
  • HMO
  • Medicare Managed Care
  • POS
  • PPO

Emblem/GHI

  • Medicare Managed Care
  • PPO

Emblem/HIP

  • ConnectiCare
  • EPO
  • Essential Plan
  • HMO
  • Medicare Managed Care
  • POS
  • PPO
  • Select Care (Exchange)
  • Vytra

Empire Blue Cross/Blue Shield

  • Medicare Managed Care

Empire Blue Cross Blue Shield HealthPlus

  • Child/Family Health Plus
  • Essential Plan

Fidelis Care

  • Medicaid Managed Care
  • Medicare Managed Care

Healthfirst

  • Child/Family Health Plus
  • Leaf (Exchange)
  • Medicare Managed Care

Local 1199

  • Local 1199

MagnaCare (National)

  • MagnaCare

Medicare

  • Railroad
  • Traditional Medicare

Multiplan

  • Multiplan

MVP Health Care

  • Child/Family Health Plus
  • Essential Plan
  • Medicaid Managed Care

RiverSpring

  • Special Needs

UnitedHealthcare

  • Compass (Exchange)
  • Empire Plan
  • HMO
  • Medicaid (Community Plan)
  • Oxford Freedom
  • Oxford HMO
  • Oxford Liberty
  • POS
  • PPO

VNSNY CHOICE

  • SelectHealth
  • Special Needs

WellCare

  • Medicaid Managed Care
  • Medicare Managed Care

World Trade Center Health Plan

  • World Trade Center Health Plan

*Please contact the provider’s office directly to verify that your particular insurance is accepted.

Credentials & Experience

Education & Training

  • University of Milano
  • Residency: Universita Degli Studi Di Milano
  • Fellowship: Lenox Hill Hospital

Honors & Awards

  • 2004 - Associazione per la Lotta alla Trombosi Scholarship, Milan, Italy

Research

Selected Publications

  1. Basman C, Kliger CA, Kodra A, Patel NC, Scheinerman SJ, Pirelli L. Transcatheter Mitral Valve-in-Valve With Surgical Resection of Bioprosthetic Valve Leaflets Under Direct Vision (Mitral SURPLUS). JACC Cardiovasc Interv. 2022 Jun 27;15(12):e145-e146. doi: 10.1016/j.jcin.2022.04.007. Epub 2022 May 11. PMID: 35568642
  2. Vitanova K, Zaid S, Tang GHL, Kaneko T, Bapat VN, Modine T, Denti P; EXPLANT-TAVR Investigators. J Thorac Cardiovasc Surg. 2022 Mar 26:S0022-5223(22)00348-8. doi: 10.1016/j.jtcvs.2021.12.060. Online ahead of print. (*member of the investigative team cited in the appendix of manuscript). PMID: 34973908
  3. Basman C, Kodra A, Mustafa A, Rene G, Wang D, Pirelli L, Kliger CA. Percutaneous Retrieval of a Ruptured SAPIEN Ultra Balloon: The Reverse Umbrella Technique. JACC Cardiovasc Interv. 2022 Jan 24;15(2):e17-e19. doi: 10.1016/j.jcin.2021.10.028. Epub 2021 Dec 29. PMID: 34973908
  4. Li A, Basman C, Wang D, Rahming H, Lannan L, Arnone P, Mustafa A, Kodra A, Pirelli L, Uttara S, Mihelis E. TCT-360 Comparison of Outcomes Using an Overexpanded Under-sized Versus Nominal-Sized SAPIEN 3 Ultra Transcatheter Heart Valve in Patients With Borderline Annulus Area Based on Computed Tomographic Angiography. Journal of the American College of Cardiology. 2021 Nov;78(19_Supplement_S):B148-.
  5. Bapat VN, Zaid S, Fukuhara S, Saha S, Vitanova K, Kiefer P, Squiers JJ, Voisine P, Pirelli L, Wyler von Ballmoos M, Chu MWA, Rodés-Cabau J, DiMaio JM, Borger MA, Lange R, Hagl C, Denti P, Modine T, Kaneko T, Tang GHL, and EXPLANT-TAVR Investigators. Surgical Explantation After TAVR Failure: Mid-Term Outcomes From the EXPLANT-TAVR International Registry. J Am Coll Cardiol Intv. 2021 Sep, 14 (18) 1978–1991
  6. Kaneko T, Hirji S, Zaid S, Lange R, Kempfert J, Conradi L, Hagl C, Borger MA, Taramasso M, Nguyen TC, Ailawadi G, Shah AS, Smith RL, Anselmi A, Romano MA, Ali WB, Ramlawi B, Grubb KJ, Robinson NB, Pirelli L, Chu MWA, Andreas M, Obadia JF, Gennari M, Garatti A, Tchetche D, Nazif TM, Bapat VN, Modine T, Denti P, Tang GHL, and CUTTING-EDGE Investigators. Mitral Valve Surgery After Transcatheter Edge-to-Edge Repair: Mid-Term Outcomes From the CUTTING-EDGE International Registry. J Am Coll Cardiol Intv. 2021 Sep, 14 (18) 2010–2021
  7. Basman C, Wang D, Pirelli L, El-Haddad H, Mihelis EA, Mehla P, Patel NC, Scheinerman SJ, Trost B, Kliger CA. CTA-Fluoroscopy Fusion Imaging for the Guidance of Cerebral Embolic Protection: Pro-Fusion Rather Than Con-Fusion. JACC Cardiovasc Interv. 2021 Aug 9;14(15):1736-1738. doi: 10.1016/j.jcin.2021.04.030. PMID: 34353605
  8. Pirelli L, Basman CL, Brinster DR, Wang D, Patel N, Scheinerman SJ, Kliger CA. Surgical Resection of Prosthetic Valve Leaflets Under Direct Vision (SURPLUS) for Redo TAVR. JACC Cardiovasc Interv. 2021 Apr 8:S1936-8798(21)00336-8. doi: 10.1016/j.jcin.2021.02.026. PMID: 33865740
  9. Pirelli L, Hong E, Steffen R, Vahl TP, Kodali SK, Bapat V. Mitral valve-in-valve and valve-in-ring: tips, tricks, and outcomes. Ann Cardiothorac Surg. 2021;10(1):96-112. doi:10.21037/acs-2019-mv-169. PMID: 33575180
  10. Basman C, Seetharam K, Johnson J, Hemli JM, Brinster DR, Patel NC, Jacob Scheinerman S, Kliger CA, Pirelli L. Preoperative multidetector computed tomography for isolated surgical aortic valve replacement: Planning for future transcatheter options. J Card Surg. 2020 Sep 29. doi: 10.1111/jocs.15080. Epub ahead of print. PMID: 32996186
  11. Basman C, Seetharam K, Pirelli L, Kliger CA. Transcatheter aortic valve-in-valve-in-valve implantation with three-dimensional printing guidance: A case report. J Card Surg. 2020 Jul;35(7):1676-1680. doi: 10.1111/jocs.14614. Epub 2020 May 5. PMID: 32369868
  12. Basman C, Kliger CA, Pirelli L, Scheinerman SJ. Management of elective aortic valve replacement over the long term in the era of COVID-19. Eur J Cardiothorac Surg. 2020 Jun 1;57(6):1029-1031. doi: 10.1093/ejcts/ezaa152. PMID: 32301976
  13. Basman C, Hemli JM, Kim MC, Seetharam K, Brinster DR, Pirelli L, Kliger CA, Scheinerman SJ, Singh VP, Patel NC. Long-term survival in triple-vessel disease: Hybrid coronary revascularization compared to contemporary revascularization methods. J Card Surg. 2020 Jul 28. doi: 10.1111/jocs.14891. Online ahead of print. PMID: 32725629
  14. Patel NC, Hemli JM, Seetharam K, Singh VP, Scheinerman SJ, Pirelli L, Brinster DR, Kim MC. Minimally invasive coronary bypass versus percutaneous coronary intervention for isolated complex stenosis of the left anterior descending coronary artery. J Thorac Cardiovasc Surg. 2020 May 29:S0022-5223(20)31256-3. doi: 10.1016/j.jtcvs.2020.04.171. Online ahead of print. PMID: 32653282
  15. Pirelli L, Patel NC, Scheinerman JS, Brinster DR, Hemli JM, Basman C, Kliger CA. Hybrid Minimally Invasive Approach for Combined Obstructive Coronary Artery Disease and Severe Aortic Stenosis. Innovations (Phila). 2020 Mar/Apr;15(2):131-137. doi: 10.1177/1556984519896581. Epub 2020 Jan 1. PMID: 31893954
  16. Patel NC, Hemli JM, Seetharam K, Graver LM, Brinster DR, Pirelli L, Scheinerman SJ, Hartman AR. Reoperative mitral valve surgery via sternotomy or right thoracotomy: A propensity-matched analysis. J Card Surg. 2019 Oct;34(10):976-982. doi: 10.1111/jocs. 14170. Epub 2019 Aug 2. PMID: 31376216
  17. Patel NC, Hemli JM, Kim MC, Seetharam K, Pirelli L, Brinster DR, Scheinerman SJ, Singh VP. Short- and intermediate-term outcomes of hybrid coronary revascularization for double-vessel disease. J Thorac Cardiovasc Surg. 2018 Nov;156(5):1799-1807.e3. doi: 10.1016/j.jtcvs.2018.04.078. Epub 2018 Apr 30. PMID: 30119899
  18. Pirelli L, Scheinerman JS, Brinster DR, Patel NC, Eltom A, Hemli JM, Kliger CA. Transinnominate approach for transcatheter aortic valve replacement: single-centre experience of minimally invasive alternative access. Eur J Cardiothorac Surg. 2018 Mar 1;53(3):545-551. doi: 10.1093/ejcts/ezx361. PMID: 29048474
  19. Al Badri A, Kliger C, Weiss D, Pirelli L, Wilson S, DeLaney ER, Jelnin V, Kronzon I, Perk G, Hemli JM, Patel NC, Raoof S, Ruiz CE.  Right atrial vacuum-assisted thrombectomy: single center experience.  J Invasive Cardiol. 2016 May;28(5):196-201. PMID: 27145051
  20. Gulkarov I, Bohmann K, Cinnante KM, Pirelli L, Yu PJ, Grau JB, Pintucci G, Galloway AC, Mignatti P. Topical mitogen-activated protein kinases inhibition reduces intimal hyperplasia in arterialized vein grafts. J Surg Res. 2009 Jun 1;154(1):150-6. doi: 10.1016/j.jss.2008.04.025. Epub 2008 May 9. PMID: 18805551

Other Peer-Reviewed Publications

  1. Basman C, Pirelli L, Singh VP, Reimers CD, Hemli J, Brinster DR, Patel NC, Scheinerman SJ, Kliger CA. Lifetime management for aortic stenosis: Planning for future therapies. J Cardiol. 2022 Jan 8:S0914-5087(21)00365-8. doi:10.1016/j.jjcc.2021.12.010. Online ahead of print. PMID: 35016808.
  2. Ong C, Brown RM, Gershon A, Trost B, Hosseini H, Pirelli L. Mitral Arcade With Anomalous Papillary Muscles: Rare Cause of Mitral Stenosis in a Young Adult. JACC Case Rep. 2021 Aug 19;3(10):1303-1309. doi: 10.1016/j.jaccas.2021.06.013. eCollection 2021 Aug 18. PMID: 34471883
  3. Basman C, Johnson J, Pirelli L, Patel NC, Reimers C, Singh VP, Scheinerman SJ, Kliger CA. Mitral Regurgitation in the High-Risk Patient: Integrating an Expanding Armamentarium of Transcatheter Devices into the Treatment Algorithm. Cardiol Rev. 2021 Aug 9. doi: 10.1097/CRD.0000000000000412. Online ahead of print. PMID: 34380944
  4. Spring AM, Pirelli L, Basman CL, Kliger CA. The importance of pre-operative imaging and 3-D printing valve-in-valve replacement. Cardiovasc Revasc Med. 2020 Jul 28:S1553-8389(20)30457-7. doi. 10.1016/j.carrev.2020.07.031. Online ahead of print. PMID: 32798117
  5. Hemli JM, Uppal SK, Seetharam K, Delianides J, Pirelli L, Scheinerman SJ, Patel NC. Galactorrhea Following Minimally Invasive Reoperative Mitral Valve Replacement: An Unexpected Complication. Innovations (Phila). 2020 Mar/Apr;15(2):177-179. doi: 10.1177/1556984520909800. PMID: 32352899
  6. Ferrari E, Gallo M, Wang C, Zhang L, Taramasso M, Maisano F, Pirelli L, Berdajs D, von Segesser LK. Three-dimensional printing in adult cardiovascular medicine for surgical and transcatheter procedural planning, teaching and technological innovation. Interact Cardiovasc Thorac Surg. 2020 Feb 1;30(2):203-214. PMID: 31633170
  7. Kanjanauthai S, Pirelli L, Nalluri N, Kliger CA. Subclinical leaflet thrombosis following transcatheter aortic valve replacement. J Interv Cardiol. 2018 Oct;31(5):640-647. doi: 10.1111/joic.12521. Epub 2018 May 23. PMID: 29790209
  8. Pirelli L, Kliger CA, Patel NC, Bono M, Ruiz CE, Jelnin V, Fontana GP. Minimally Invasive Robotically Assisted Repair of Partial Anomalous Venous Connection. Innovations (Phila). 2017 Jan/Feb;12(1):71-73. doi: 10.1097/IMI.0000000000000323. PMID: 27918317
  9. Pirelli L, Kliger C, Fontana GP, Ruiz CE. Direct percutaneous transaortic approach for treatment of aortic pseudoaneurysms. Interact Cardiovasc Thorac Surg. 2015 May;20(5):680-1. doi: 10.1093/icvts/ivv027. Epub 2015 Feb 23. PMID: 25712986
  10. Weiss D, Ruiz CE, Pirelli L, Jelnin V, Fontana GP, Kliger C. Available transcatheter aortic valve replacement technology. Curr Atheroscler Rep. 2015 Mar;17(3):488. doi: 10.1007/s11883-015-0488-7. PMID: 25651785
  11. Pirelli L, Yu PJ, Srichai MB, Khvilivitzky K, Angelini P, Grau JB. Ectopic origin of left coronary ostium from left ventricle, with occlusive membrane: a previously unreported anomaly, with an embryologic interpretation. Tex Heart Inst J. 2008;35(2):162-5. PMID: 18612445
  12. Yu PJ, Ferrari G, Pirelli L, Gulkarov I, Galloway AC, Mignatti P, Pintucci G. Vascular injury and modulation of MAPKs: a targeted approach to therapy of restenosis. Cell Signal. 2007 Jul;19(7):1359-71. doi: 10.1016/j.cellsig.2007.03.002. Epub 2007 Mar 15. PMID: 17448633
  13. Comerio G, Ferratini M, Pezzano A, Racca V, Tavanelli M, Pirelli L, Fundarò P, Mattioli R, Donatelli F. [Resection of unusual atrial mass complicated with fungal endocarditis in a patient undergoing immunosuppressive treatment]. Monaldi Arch Chest Dis. 2003 Jun;60(2):166-9. Italian. PMID: 12918171