Elaine Y Wan, MD
Overview
Dr. Elaine Wan is the Esther Aboodi Associate Professor of Medicine in Cardiology and Cardiac Electrophysiology at Columbia University Medical Center, College of Physicians and Surgeons and attending physician at NewYork-Presbyterian Hospital. She is trained in Internal Medicine, Clinical Cardiology and is an invasive cardiac electrophysiologist. She is the Director of Electrophysiology Research and oversees all electrophysiology clinical trials. She performs implantation of cardiac devices including pacemaker and defibrillators, as well as ablation of arrhythmias.
Dr. Wan is a physician-scientist and focuses on development of novel treatments for heart failure, vascular dysfunction and arrhythmias such as atrial fibrillation. She is a translational researcher also interested in development of innovative imaging modalities to improve ablation delivery. Dr. Wan is a graduate of the Massachusetts Institute of Technology. She received her medical degree from Columbia University College of Physicians and Surgeons and completed her fellowship in Cardiovascular Diseases and Clinical Cardiac Electrophysiology at NewYork-Presbyterian/Columbia.Dr. Wan is the recipient of numerous national and international awards including the 2016 American College of Cardiology Young Investigator Award First Place in Molecular Cellular Cardiology, 2016 Young Physician Investigator Award from the American Society of Clinical Investigators, 2016 Cardiostim/Europace Best Young EP Presentation (Nice, France) and the 2008 American Heart Association Women in Cardiology for Clinical Excellence.
She is the recipient of several competitive research grants including NIH NHLBI K08 Mentored Career Development Award, NIH NHLBI R03 Small Grant Program and NIH NHLBI R01 to study the use of 3D mitochondrial dysfunction imaging in cardiac arrhythmias. She is also a recipient of the American Heart Association Scientist Development Grant, grant support from the Foundation of Gender Specific Medicine, Columbia University Louis V. Gerstner Jr. Scholars Program, and Columbia University Provost's Grants Program for Junior Faculty who Contribute to the Diversity Goals of the University. She is vice co-chair of the Heart Rhythm Society Digital Health Committee and a member of the American Heart Association Committee on Electrocardiography and Arrhythmias. She has published over 77 manuscripts in high impact journals such as Nature Medicine, Circulation Research, Journal of Clinical Investigation and Journal of American College of Cardiology. She has written 3 book chapters and given invited talks around the world.
Areas of Expertise / Conditions Treated
- Arrhythmia Management
- Cardiac Electrophysiology
- Cardiac Resynchronization
- Cardioversion
- Diagnostic Electrophysiology Study
- Electrophysiology-Arrhythmias
- Heart Disease and Women
- Holter Monitor
- Implant Cardiac Defibrillator
- Tachycardia
Academic Appointments
- Esther Aboodi Assistant Professor of Cardiology (in Medicine)
Hospital Affiliations
- NewYork-Presbyterian / Columbia University Irving Medical Center
Languages
- Cantonese
- Mandarin
- Spanish
Gender
- Female
Schedule an Appointment
Virtual Visits/Telehealth
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Phone Appointments
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Location(s)
Insurance Accepted
Aetna
- Aetna Signature Administrators
- EPO
- HMO
- Medicare Managed Care
- NYP Employee Plan
- NY Signature
- PPO
- Student Health
Affinity Health Plan
- Essential Plan
- Medicaid Managed Care
Amerigroup of New Jersey
- New Jersey Services (Medicaid Managed Care)
Cigna
- EPO
- Great West (National)
- HMO
- Medicare Managed Care
- POS
- PPO
Emblem/GHI
- Medicare Managed Care
- PPO
Emblem/HIP
- ConnectiCare
- EPO
- Essential Plan
- HMO
- Medicare Managed Care
- POS
- PPO
- Select Care (Exchange)
- Vytra
Empire Blue Cross Blue Shield HealthPlus
- Child/Family Health Plus
- Essential Plan
Fidelis Care
- Child/Family Health Plus
- Medicaid Managed Care
- Medicare Managed Care
Healthfirst
- Child/Family Health Plus
- Leaf (Exchange)
- Medicare Managed Care
Local 1199
- Local 1199
MagnaCare (National)
- MagnaCare
Medicare
- Railroad
- Traditional Medicare
Multiplan
- Multiplan
MVP Health Care
- Child/Family Health Plus
- Essential Plan
- Medicaid Managed Care
Quality Health Management
- Quality Health Management
RiverSpring
- Special Needs
UnitedHealthcare
- Compass (Exchange)
- Empire Plan
- HMO
- Medicaid (Community Plan)
- Oxford Freedom
- Oxford HMO
- Oxford Liberty
- POS
- PPO
VNSNY CHOICE
- SelectHealth
WellCare
- Medicare Managed Care
- New Jersey Services (Medicaid Managed Care)
World Trade Center Health Plan
- World Trade Center Health Plan
Credentials & Experience
Education & Training
- MD, Columbia University College of Physicians and Surgeons
- 2005 Columbia University College of Physicians and Surgeons
- Residency: NewYork-Presbyterian Hospital/Columbia University Medical Center
- Fellowship: NewYork-Presbyterian Hospital/Columbia University Medical Center
Board Certifications
- Cardiovascular Disease
- Clinical Cardiac Electrophysiology
- Internal Medicine
Honors & Awards
- 2017 - Present - Fellow of the Heart Rhythm Society
- 2016 American College of Cardiology Young Investigator Award First Place in Molecular Cellular Cardiology
- 2016 Young Physician Investigator Award from the American Society of Clinical Investigators
- 2016 Cardiostim Best Young EP Presentation Award (Europace, Nice, France)
- 06/2010 - 06/2011 - President, American Heart Association Fellows Society of New York
- 06/2008 – Present - American Heart Association Women in Cardiology Trainee Award for Clinical Excellence
- 05/2008 – Present - American Medical Association Seed Grant Recipient
- 06/2008 – Present - Fellow of the American College of Cardiology
- 05/2008 – Present - Fellow of the American Heart Association
- 06/2010 – Present - American Society of Echocardiography
- 06/2011 – Present - Heart Rhythm Society
- 06/2011 – Present - Society of Cardiovascular Computed Tomography
Research
Research Interests
- Biophysics of ablation and novel imaging modalities to improve clinical delivery of ablation lesions
- Cardiovascular disease and arrhythmias in women
- Endothelial dysfunction due to electrophysiological changes in heart failure
- Role of vascular ion channels in heart failure
Grants
Lewis Katz Cardiovascular Research Prize
07/2017 - 07/2018
Principal Investigator
Columbia Biomedical Accelerator (formerly the Columbia-Coulter Translational Research Partnership) Award
Visiblate: Real time ablation lesion visualization
07/2017 - 07/2018
Co-Principal Investigator
M. Irené Ferrer Scholar Award in Gender-Specific Medicine
Understanding gender differences in atrial fibrillation using a novel transgenic mouse model
04/2017- 04/2018
Principal Investigator
NIH-NHLBI K08 Mentored Career Development Award
Role of Vascular Ion Channels in Heart Failure and Cardiovascular Diseases
9/2015-9/2020
Principal Investigator
5K08HL122526 - 02
American Heart Association Scientist Development Grant National Center
Role of Vascular Ion Channels in Heart Failure (returned)
7/2015 - 7/2019
Principal Investigator
Columbia University Provost’s Grants Program for Junior Faculty who Contribute to the Diversity Goals of the University
Understanding gender differences in atrial fibrillation using a novel transgenic mouse model
07/2014 - 07/2015
Principal Investigator
Columbia University Louis V. Gerstner Jr. Scholars Program 2014
Role of Vascular Ion Channels in Heart Failure
07/2014 - 07/2017
Principal Investigator
NIH CTSA Irving Institute Clinical Trials Office Pilot Grant
Roles of Vascular Ion Channels in Heart Failure
07/2013 - 07/2014
Principal Investigator
Selected Publications
Publications
1. Wan E, Abrams J, Weinberg RL, Katchman A, Bayne J, Zakharov S, Yang L, Morrow JP, Garan H, Marx S. Aberrant sodium influx is sufficient to cause cardiomyopathy and spontaneous sustained atrial fibrillation in mice. JCI. 2015; November 23, 4-11. Epub ahead of print.
2. Wan E, Dizon J Whang W, Garan H. Parsing a perplexing paroxysmal pathway. Heart Rhythm Case Reports. 2015; 1(6). 453-456.
3. Wan E and Boyden P. A matter of fat: lipids as an antiarrhythmic. Circulation: Arrhythmia and Electrophysiology. 2015. Dec;8(6): 1313-5
4. Provost J, Costet A, Wan E, Gambhir A, Whang W, Garan H, Konofagou EE. Assessing the atrial electromechanical coupling during atrial focal tachycardia, flutter, and fibrillation using electromechanical wave imaging in humans. Comput Bio Med. 2015. Oct 1;65:161-7.
5. Adams T, Wan E, Wei Y, Wahab R, Castagna F, Wang G, Emin M, Russo C, Homma S, Le Jemtel TH, Jelic S. Secondhand smoking is associated with vascular inflammation. Chest. 2015; March 5. Epub ahead of print.
6. Grondin J, Wan E, Gambhir A, Garan H, Konofagou E. Intracardiac myocardial elastography in canines and humans in vivo. IEEE Trans Ultrason Ferroelectr Freq Control. 2015; 62(2):337-49.
7. Yang L, Katchman A, Weinberg RL, Abram J, Samad T, Wan E, Pitt G, Marx SO. The PDZ Motif of α1C Subunit is not Required for Surface Trafficking and Adrenergic Modulation of CaV1.2 in Heart. Journal of Biological Chemistry. 2015. Jan 23;290(4):2166-74.
8. Wan E, Yeap XY, Dehn S, Terry RL, Novak ML, Zhang S, Iwata S, Han X, Homma S, Drosatos K, Lomasney JW, Engman DM, Miller SD, Vaughan DE, Morrow JP, Kishore, R Thorp EB. Enhanced efferocytosis of apoptotic cardiomyocytes through myeloid-epithelial-reproductive tyrosine kinase links acute inflammation resolution to cardiac repair after infarction. Circulation Research. 2013; 113(8): 1004-1012.
9. Huang H, Amin V, Gurin M, Wan E, Thorp E. Homma, S, Morrow J. Diet-induced obesity causes long QT and reduces transcription of voltage-gated potassium channels. J Molec Cell Card. 2013; 59: 151-158.
10. Wan E, Kusher J, Zakharov S, Nui X, Chudasama N, Kelly C, Waase M, Doshi D, Liu G, Iwata S, Takyuki S, Katchman A, D'Armiento J, Homma S, Marx, S. Reduced vascular BK channel currents underlie heart failure-induced vasoconstriction in mice. FASEB J. 2013; 27(5):1859-1867.
11. Ganda, A., Onat, D., Demmer, RT., Wan, E., Vittorio, TJ., Sabbah, HN.., Colombo, PC., Venous congestion and endothelial activation in acute decompensated heart failure. Curr Heart Fail Rep. 2010; 7(2): 66-74.
12. Vigilance DW, Garrido M, Williams M, Wan E, Zeidner A, Casher J, Zheng K, Kherani AR, Morgan JA, Oz MC, Argenziano M.: Off-pump epicardial atrial fibrillation surgery utilizing a novel bipolar radiofrequency system. Heart Surgery Forum 2006; 9: E803-806.
13. Kherani AR, John R, Cheema FH, Naka Y, Fal J, Garrido MJ, Morgan J, Vigilance D, Edwards NM, Wan E, Oz MC.: A Decade of Improvement in Cardiac Transplantation. Circulation. 2003; 107: 35.
14. Cauwels, A., Wan, E., Leismann, M., & Tuomanen, E.I. : Coexistence of CD-14 Dependent and Independent Pathways for Stimulation of Human Monocytes by Gram-Positive Bacteria. Infection and Immunity 1997; 65: 3255-3260.
Abstracts
1. Wan E, Grondin J, Biviano A, Whang W, Gambhir A, Konofagou E, Garan H. Novel Method Using Intracardiac Myocardial Elastography Provides Real-time Assessment of Right and Left Atrial Radiofrequency Ablation in Humans. American Heart Association, November 15-19, 2014. Poster Presentation. Chicago, Illinois.
2. Wan E, Bucciarellia L, Mecklai A, Klapholz M, Jelic S, Onat D, Adams T, LeJemtel T, Jorde U, Konstam M, Colombo P. Increased Nitric Oxide Degradation by Oxidative Stress and Decreased Nitric Oxide Production by Endothelial Nitric Oxide Synthase Cause Severe Derangement of Venous Nitric Oxide Balance in Decompensated Heart Failure. American College of Cardiology. March 2009. Poster Presentation. Orlando, Florida.
3. Jelic, S, Wan E, Adams T, Padeletti M, Bucciarelli L, Colombo P, Factor P, LeJemtel T. Direct Evidence of Adverse Effects of Smoking on Vascular Endothelium. American Thoracic Society. May 19-21, 2008. Poster Presentation. Toronto, Canada.
4. Okrasinski SJ, Wan EY, Lee W-N, Oe Y, and Konofagou EE. Early Detection of Coronary Stenosis with Myocardial Elastography: A Clinical Feasibility Study. IEEE International Ultrasonics Symposium. Oct 11-14, 2010. Oral Presentation. San Diego, CA.
For a complete list of publications, please visit PubMed.gov